IL-19 Antikörper (C-Term)

Produktnummer ABIN2789719

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch IL-19 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Hund, Rind (Kuh) und Schwein.

Kurzübersicht für IL-19 Antikörper (C-Term) (ABIN2789719)

Target: IL-19 (IL19) (Interleukin 19 (IL19))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IL-19 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: IL19 Antibody - C-terminal region

Sequenz: KILRKISSIA NSFLYMQKTL RQCQEQRQCH CRQEATNATR VIHDNYDQLE

Homologie: Cow: 93%, Dog: 79%, Human: 100%, Mouse: 85%, Pig: 93%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against IL19. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human IL19

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64070-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu IL-19

Target: IL-19 (IL19) (Interleukin 19 (IL19))

Andere Bezeichnung: IL19

Hintergrund:

Background Information: The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.

Gene Name: interleukin 19

Alternative Symbols: MDA1, NG.1, ZMDA1, IL-10C

Protein Name: Interleukin 19 EMBL CAH71814.1

Molekulargewicht: 23kDa

Gen-ID: 29949

NCBI Accession: NP_715639

UniProt: Q5VUT3