IL-19 Antikörper (AA 51-100)

Produktnummer ABIN7229104

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch IL-19 in WB, IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für IL-19 Antikörper (AA 51-100) (ABIN7229104)

Target: IL-19 (IL19) (Interleukin 19 (IL19))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-IL-19 Antikörper

Bindungsspezifität: AA 51-100

Verwendungszweck: Rabbit Anti-IL-19 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of IL-19

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human IL-19 protein at AA range: 51-100

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:500-200,ELISA 1:10000-20000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu IL-19

Target: IL-19 (IL19) (Interleukin 19 (IL19))

Andere Bezeichnung: IL-19

Hintergrund: Interleukin-19, IL-19, Melanoma differentiation-associated protein-like protein, NG.1The protein encoded by IL19 is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. IL19 (Interleukin 19) is a Protein Coding gene. Diseases associated with IL19 include Spongiotic Dermatitis and Psoriasis. Among its related pathways are Akt Signaling and PEDF Induced Signaling.

Molekulargewicht: 20kD

Gen-ID: 29949

UniProt: Q9UHD0