PRKAG3 Antikörper (N-Term)

Produktnummer ABIN2789710

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PRKAG3 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PRKAG3 Antikörper (N-Term) (ABIN2789710)

Target: PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRKAG3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PRKAG3 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PRKAG3 Antibody - N-terminal region

Sequenz: ENSSSWPSPA VTSSSERIRG KRRAKALRWT RQKSVEEGEP PGQGEGPRSR

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PRKAG3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64048-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PRKAG3

Target: PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))

Andere Bezeichnung: PRKAG3

Hintergrund:

Targeted Subunit: gamma-3

Background Information: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.

Gene Name: Protein kinase, AMP-activated, gamma 3 non-catalytic subunit

Alternative Symbols: AMPKG3, SMGMQTL

Protein Name: 5'-AMP-activated protein kinase subunit gamma-3

Molekulargewicht: 54kDa

Gen-ID: 53632

NCBI Accession: NP_059127

UniProt: Q9UGI9

Pathways: AMPK Signaling, Cellular Glucan Metabolic Process, Warburg Effekt