Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

PDE6B Antikörper (C-Term)

PDE6B Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2789553
  • Target Alle PDE6B Antikörper anzeigen
    PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
    Bindungsspezifität
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 14
    • 10
    • 8
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen
    Wirt
    • 14
    • 1
    Kaninchen
    Klonalität
    • 15
    Polyklonal
    Konjugat
    • 13
    • 1
    • 1
    Dieser PDE6B Antikörper ist unkonjugiert
    Applikation
    • 12
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    RQHEHVIHLM DIAIIATDLA LYFKKRAMFQ KIVDESKNYQ DKKSWVEYLS
    Homologie
    Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PDE6B. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Top Product
    Discover our top product PDE6B Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 854 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
    Andere Bezeichnung
    PDE6B (PDE6B Produkte)
    Synonyme
    CSNB3 antikoerper, CSNBAD2 antikoerper, PDEB antikoerper, RP40 antikoerper, rd1 antikoerper, PDBS antikoerper, RCD-1 antikoerper, Pdeb antikoerper, r antikoerper, rd antikoerper, rd-1 antikoerper, rd10 antikoerper, phosphodiesterase 6B antikoerper, phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide antikoerper, PDE6B antikoerper, Pde6b antikoerper
    Hintergrund
    Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: CSNB3, CSNBAD2, PDEB, RP40, rd1
    Protein Interaction Partner: PPP1CC,
    Protein Size: 854
    Molekulargewicht
    98 kDa
    Gen-ID
    5158
    NCBI Accession
    NM_001145292, NP_001138764
    UniProt
    E7ETT3
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
Sie sind hier:
Kundenservice