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PDE6B Antikörper

PDE6B Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7262851
  • Target Alle PDE6B Antikörper anzeigen
    PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
    Reaktivität
    • 14
    • 10
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 14
    • 1
    Kaninchen
    Klonalität
    • 15
    Polyklonal
    Konjugat
    • 13
    • 1
    • 1
    Dieser PDE6B Antikörper ist unkonjugiert
    Applikation
    • 13
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human PDE6B (NP_001138763.1).
    Isotyp
    IgG
    Top Product
    Discover our top product PDE6B Primärantikörper
  • Applikationshinweise
    IHC 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))
    Andere Bezeichnung
    PDE6B (PDE6B Produkte)
    Synonyme
    CSNB3 antikoerper, CSNBAD2 antikoerper, PDEB antikoerper, RP40 antikoerper, rd1 antikoerper, PDBS antikoerper, RCD-1 antikoerper, Pdeb antikoerper, r antikoerper, rd antikoerper, rd-1 antikoerper, rd10 antikoerper, phosphodiesterase 6B antikoerper, phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide antikoerper, PDE6B antikoerper, Pde6b antikoerper
    Hintergrund
    Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
    Gen-ID
    5158
    UniProt
    P35913
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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