HTRA1 Antikörper (N-Term)

Produktnummer ABIN2789539

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HTRA1 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh) und Schwein.

Kurzübersicht für HTRA1 Antikörper (N-Term) (ABIN2789539)

Target: HTRA1 (HtrA Serine Peptidase 1 (HTRA1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HTRA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-HTRA1 Antikörper

Bindungsspezifität: N-Term

Sequenz: DANTYANLCQ LRAASRRSER LHRPPVIVLQ RGACGQGQED PNSLRHKYNF

Homologie: Cow: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against HTRA1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 480 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HTRA1

Target: HTRA1 (HtrA Serine Peptidase 1 (HTRA1))

Andere Bezeichnung: HTRA1

Hintergrund: This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7.
Alias Symbols: ARMD7, HtrA, L56, ORF480, PRSS11
Protein Interaction Partner: FAM46A, IMPDH1, CSNK2B, NOS3, APOE, XIAP, PARD6B, LRP10, FCHSD2, CDYL, COX5A, GOLGA2, GDF5, COL3A1, COL1A1, COL2A1, CAST, BMP4,
Protein Size: 480

Molekulargewicht: 53 kDa

Gen-ID: 5654

NCBI Accession: NM_002775, NP_002766

UniProt: Q92743

Pathways: Growth Factor Binding