RGR Antikörper (C-Term)

Produktnummer ABIN2789477

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RGR in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Pferd und Schwein.

Kurzübersicht für RGR Antikörper (C-Term) (ABIN2789477)

Target: RGR (Retinal G Protein Coupled Receptor (RGR))

Reaktivität: Human, Maus, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RGR Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: RGR Antibody - C-terminal region

Sequenz: GKSGHLQVPA LIAKMVPTIN AINYALGNEM VCRGIWQCLS PQKREKDRTK

Homologie: Horse: 83%, Human: 100%, Mouse: 85%, Pig: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against RGR. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63386-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu RGR

Target: RGR (Retinal G Protein Coupled Receptor (RGR))

Andere Bezeichnung: RGR

Hintergrund:

Background Information: This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively).

Gene Name: Retinal G protein coupled receptor

Alternative Symbols: RP44

Protein Name: RPE-retinal G protein-coupled receptor

Molekulargewicht: 28kDa

Gen-ID: 5995

NCBI Accession: NP_001012740

UniProt: P47804