PD-L1 Antikörper (C-Term)
Kurzübersicht für PD-L1 Antikörper (C-Term) (ABIN2789466)
Target
Alle PD-L1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- NVTSTLRINT TTNEIFYCTF RRLDPEENHT AELVIPELPL AHPPNERTHL
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Homologie
- Cow: 79%, Human: 100%, Pig: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CD274. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 290 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PD-L1 (CD274 (PD-L1))
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Andere Bezeichnung
- CD274
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Hintergrund
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CD274 is involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
Alias Symbols: B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1, PDCD1LG1, PDL1
Protein Interaction Partner: PDCD1, CD80, PTPN11,
Protein Size: 290 -
Molekulargewicht
- 32 kDa
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Gen-ID
- 29126
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NCBI Accession
- NM_014143, NP_054862
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UniProt
- Q9NZQ7
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Pathways
- Cancer Immune Checkpoints
Target
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