CD82 Antikörper (C-Term)

Produktnummer ABIN2789464

Dieses Anti-CD82-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CD82 in WB. Geeignet für Human und Saccharomyces cerevisiae.

Kurzübersicht für CD82 Antikörper (C-Term) (ABIN2789464)

Target: CD82

Reaktivität: Human, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD82 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD82 Antikörper

Bindungsspezifität: C-Term

Sequenz: DYVQAQVKCC GWVSFYNWTD NAELMNRPEV TYPCSCEVKG EEDNSLSVRK

Homologie: Human: 100%, Yeast: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CD82. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 267 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CD82

Target: CD82

Andere Bezeichnung: CD82

Hintergrund: This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: 4F9, C33, GR15, IA4, KAI1, R2, SAR2, ST6, TSPAN27
Protein Interaction Partner: GGT1, CD81, CD53, UBC, LGALS3BP, AMFR, VANGL1, IGSF8, ITGA3, NUP88, PTGFRN, ITGB2, ITGA4, ERBB3, CD4, ERBB2, CD63, ITGA6, HLA-DRA, HLA-DMB, HLA-DMA, ITGB1, EGFR, HBEGF, CANX, LRP1, CD19, ITGAL, HLA-DOB, CD46, CD151, CD9, RUVBL1, POLR2A, KAT5, CTNNB1, RUVB
Protein Size: 267

Molekulargewicht: 29 kDa

Gen-ID: 3732

NCBI Accession: NM_002231, NP_002222

UniProt: P27701

Pathways: p53 Signalweg