UCP1 Antikörper (N-Term)

Produktnummer ABIN2789412

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch UCP1 in WB. Es zeigt Reaktivität gegenüber Proben von Human und Kaninchen.

Kurzübersicht für UCP1 Antikörper (N-Term) (ABIN2789412)

Target: UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))

Reaktivität: Human, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UCP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-UCP1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: UCP1 Antibody - N-terminal region

Sequenz: GLPAGLQRQI SSASLRIGLY DTVQEFLTAG KETAPSLGSK ILAGLTTGGV

Homologie: Human: 100%, Rabbit: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against UCP1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63204-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu UCP1

Target: UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))

Andere Bezeichnung: UCP1

Hintergrund:

Background Information: Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.

Gene Name: Uncoupling protein 1 (mitochondrial, proton carrier)

Alternative Symbols: UCP, SLC25A7

Protein Name: Mitochondrial brown fat uncoupling protein 1

Molekulargewicht: 34kDa

Gen-ID: 7350

NCBI Accession: NP_068605

UniProt: P25874

Pathways: Proton Transport, Brown Fat Cell Differentiation