FGF8 Antikörper (Middle Region)
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- Target Alle FGF8 Antikörper anzeigen
- FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FGF8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LIVETDTFGS RVRVRGAETG LYICMNKKGK LIAKSNGKGK DCVFTEIVLE
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against FGF8. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product FGF8 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 233 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
- Andere Bezeichnung
- FGF8 (FGF8 Produkte)
- Synonyme
- Aigf antikoerper, Fgf-8 antikoerper, AIGF antikoerper, FGF-8 antikoerper, HBGF-8 antikoerper, HH6 antikoerper, KAL6 antikoerper, fibroblast growth factor 8 antikoerper, Fgf8 antikoerper, FGF8 antikoerper
- Hintergrund
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The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants.
Alias Symbols: AIGF, HBGF-8, KAL6, MGC149376, FGF-8
Protein Interaction Partner: FGFR2, FGFR1, FGFR4, FGFR3, AR,
Protein Size: 233 - Molekulargewicht
- 24 kDa
- Gen-ID
- 2253
- NCBI Accession
- NM_033164, NP_149354
- UniProt
- P55075
- Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Dopaminergic Neurogenesis
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