Angiopoietin 2 Antikörper (Middle Region)

Produktnummer ABIN2789397

Der Kaninchen Polyklonal anti-Angiopoietin 2 Antikörper (ABIN2789397) detektiert spezifisch Angiopoietin 2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Kaninchen, Schwein, Rind (Kuh), Hund, Meerschweinchen, Pferd und Schaf.

Kurzübersicht für Angiopoietin 2 Antikörper (Middle Region) (ABIN2789397)

Target: Angiopoietin 2 (ANGPT2)

Reaktivität: Human, Maus, Ratte, Kaninchen, Schwein, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Angiopoietin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Angiopoietin 2 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: Angpt2 Antibody - middle region

Sequenz: NQTTRLELQL LQHSISTNKL EKQILDQTSE INKLQNKNSF LEQKVLDMEG

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against Angpt2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Angpt2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63170-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Angiopoietin 2

Target: Angiopoietin 2 (ANGPT2)

Andere Bezeichnung: Angpt2

Hintergrund:

Background Information: Angpt2 binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. It can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

Gene Name: angiopoietin 2

Alternative Symbols: An, Ang, Ang2, Agpt2, Ang-2

Protein Name: Angiopoietin-2

Molekulargewicht: 56kDa

Gen-ID: 11601

NCBI Accession: NP_031452

UniProt: O35608

Pathways: RTK Signalweg