Dieses Anti-Angiopoietin 2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Angiopoietin 2 in WB. Geeignet für Human, Maus, Ratte, Schwein, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd und Schaf.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeat freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target
Angiopoietin 2 (ANGPT2)
Andere Bezeichnung
Angpt2
Hintergrund
Angpt2 binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. It can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. Alias Symbols: Agpt2, Ang-2, Ang2 Protein Size: 496