SPARC Antikörper (C-Term)
Kurzübersicht für SPARC Antikörper (C-Term) (ABIN2789396)
Target
Alle SPARC Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- LAPLRAPLIP MEHCTTRFFE TCDLDNDKYI ALDEWAGCFG IKQKDIDKDL
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Homologie
- Cow: 93%, Dog: 86%, Goat: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 92%, Sheep: 93%, Zebrafish: 77%
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Produktmerkmale
- This is a rabbit polyclonal antibody against SPARC. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 303 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "SPARC overexpression combined with radiation retards angiogenesis by suppressing VEGF-A via miR‑410 in human neuroblastoma cells." in: International journal of oncology, Vol. 49, Issue 4, pp. 1394-406, (2016) (PubMed).
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: "SPARC overexpression combined with radiation retards angiogenesis by suppressing VEGF-A via miR‑410 in human neuroblastoma cells." in: International journal of oncology, Vol. 49, Issue 4, pp. 1394-406, (2016) (PubMed).
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- SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))
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Andere Bezeichnung
- SPARC
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Hintergrund
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Secreted protein acidic and rich in cysteine/osteonectin/BM40, or SPARC, is a matrix-associated protein that elicits changes in cell shape, inhibits cell-cycle progression, and influences the synthesis of extracellular matrix (ECM).
Alias Symbols: ON
Protein Interaction Partner: UBQLN1, ZNF579, XRCC6, CTSK, VEGFA, TGM2, TGFB1, THBS1, SPARC, PDGFA, PLAT, PLG, HSPG2, SDC2, FN1, COL13A1, COL3A1, COL1A2, COL1A1, COL2A1, PDGFB, COL5A1,
Protein Size: 303 -
Molekulargewicht
- 35 kDa
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Gen-ID
- 6678
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NCBI Accession
- NM_003118, NP_003109
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UniProt
- P09486
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Pathways
- Autophagie
Target
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