Angiopoietin 1 Antikörper (N-Term)

Produktnummer ABIN2789374

Der Kaninchen Polyklonal anti-Angiopoietin 1 Antikörper wird verwendet zum Nachweis von Angiopoietin 1 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen und Schwein. Er wurde validiert für WB.

Kurzübersicht für Angiopoietin 1 Antikörper (N-Term) (ABIN2789374)

Target: Angiopoietin 1 (ANGPT1)

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Angiopoietin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Angiopoietin 1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: ANGPT1 Antibody - N-terminal region

Sequenz: FAFLAAILTH IGCSNQRRSP ENSGRRYNRI QHGQCAYTFI LPEHDGNCRE

Homologie: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ANGPT1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63106-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Angiopoietin 1

Target: Angiopoietin 1 (ANGPT1)

Andere Bezeichnung: ANGPT1

Hintergrund:

Background Information: Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Name: Angiopoietin 1

Alternative Symbols: AGP1, AGPT, ANG1

Protein Name: Angiopoietin-1

Molekulargewicht: 55kDa

Gen-ID: 284

NCBI Accession: NP_001137

UniProt: Q15389

Pathways: RTK Signalweg, Glycosaminoglycan Metabolic Process