Angiopoietin 1 Antikörper (N-Term)

Produktnummer ABIN2789374

Produktdetails anti-Angiopoietin 1 Antikörper

Target: Angiopoietin 1 (ANGPT1)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Rind (Kuh), Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Angiopoietin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FAFLAAILTH IGCSNQRRSP ENSGRRYNRI QHGQCAYTFI LPEHDGNCRE

Homologie: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ANGPT1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 498 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Angiopoietin 1

Target: Angiopoietin 1 (ANGPT1)

Andere Bezeichnung: ANGPT1 (ANGPT1 Produkte)

Synonyme: AGP1 antikoerper, AGPT antikoerper, ANG1 antikoerper, 1110046O21Rik antikoerper, Ang-1 antikoerper, Ang1 antikoerper, Agpt antikoerper, Agpt1 antikoerper, ang1 antikoerper, wu:fc76g06 antikoerper, ANG-1 antikoerper, angpt1 antikoerper, MGC80788 antikoerper, angiopoietin 1 antikoerper, angiopoietin 1 S homeolog antikoerper, ANGPT1 antikoerper, Angpt1 antikoerper, angpt1 antikoerper, angpt1.S antikoerper

Hintergrund: Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: AGP1, AGPT, ANG1
Protein Interaction Partner: UBC, ANGPT2, ANGPT1, TEK, ITGA5,
Protein Size: 498

Molekulargewicht: 55 kDa

Gen-ID: 284

NCBI Accession: NM_001146, NP_001137

UniProt: Q15389

Pathways: RTK Signalweg, Glycosaminoglycan Metabolic Process