PLAUR Antikörper (N-Term)

Produktnummer ABIN2789360

Produktdetails anti-PLAUR Antikörper

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLAUR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ELELVEKSCT HSEKTNRTLS YRTGLKITSL TEVVCGLDLC NQGNSGRAVT

Homologie: Human: 100%, Mouse: 82%

Produktmerkmale: This is a rabbit polyclonal antibody against PLAUR. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of PLAUR

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 335 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PLAUR

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Andere Bezeichnung: PLAUR (PLAUR Produkte)

Synonyme: Cd87 antikoerper, u-PAR antikoerper, uPAR antikoerper, CD87 antikoerper, U-PAR antikoerper, UPAR antikoerper, URKR antikoerper, Par antikoerper, Plaur3 antikoerper, uPAR-2 antikoerper, uPAR-3 antikoerper, PLAUR antikoerper, plasminogen activator, urokinase receptor antikoerper, Plaur antikoerper, PLAUR antikoerper

Hintergrund: This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
Alias Symbols: CD87, UPAR, URKR
Protein Interaction Partner: TEX101, PLAU, LYN, ELAVL1, VMA21, TXNDC17, SCAF4, SDHAF2, UBQLN2, WDHD1, SELENBP1, TBCA, PSAP, CTSA, OXCT1, NOTCH2, HDLBP, CTTN, LRP1B, SURF2, SRPX2, MMP12, IL6ST, FAP, KNG1, VTN, TYK2, PFN2, JAK1, HCK, FYN, ITGB1, EEF1A1, ITGAM, LRP1, IGF2R, ITGB2, PDGFR
Protein Size: 335

Molekulargewicht: 37 kDa

Gen-ID: 5329

NCBI Accession: NM_002659, NP_002650

UniProt: Q9GK80

Pathways: Inositol Metabolic Process