TES Antikörper (Middle Region)

Produktnummer ABIN2789357

Produktdetails anti-TES Antikörper

Target: TES (Testis Derived Transcript (3 LIM Domains) (TES))

Bindungsspezifität: Middle Region

Reaktivität: Human, Rind (Kuh), Hund, Meerschweinchen, Schaf, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TES Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: PKQMNIPGGD RSTPAAVGAM EDKSAEHKRT QYSCYCCKLS MKEGDPAIYA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 91%, Horse: 79%, Human: 100%, Pig: 93%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TES. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 421 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TES

Target: TES (Testis Derived Transcript (3 LIM Domains) (TES))

Andere Bezeichnung: TES (TES Produkte)

Hintergrund: Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.
Alias Symbols: DKFZp586B2022, MGC1146, TESS, TESS-2
Protein Interaction Partner: SUMO2, VPS25, RPRD1B, OSGEP, NAGK, HNRNPUL1, EPRS, EVL, SOCS3, SPTAN1, THADA, AHCYL1, SSSCA1, ZPR1, IGBP1, ELAVL1, UBC, ARAP1, Cep350, ENAH, SPOCK2, ACTL7A, TES, ZYX, VASP, GRIPAP1, TLN1, ACTN1, RAB8B, ACTA1, GRIP1,
Protein Size: 421

Molekulargewicht: 47 kDa

Gen-ID: 26136

NCBI Accession: NM_015641, NP_056456

UniProt: Q9UGI8