TES Antikörper (Middle Region)

Produktnummer ABIN2789357

Der Kaninchen Polyklonal Anti-TES-Antikörper wurde für WB und IHC validiert. Er ist geeignet, TES in Proben von Human, Rind (Kuh), Hund, Meerschweinchen, Schaf, Pferd und Schwein zu detektieren.

Kurzübersicht für TES Antikörper (Middle Region) (ABIN2789357)

Target: TES (Testis Derived Transcript (3 LIM Domains) (TES))

Reaktivität: Human, Rind (Kuh), Hund, Meerschweinchen, Schaf, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TES Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TES Antikörper

Bindungsspezifität: Middle Region

Sequenz: PKQMNIPGGD RSTPAAVGAM EDKSAEHKRT QYSCYCCKLS MKEGDPAIYA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 91%, Horse: 79%, Human: 100%, Pig: 93%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TES. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 421 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TES

Target: TES (Testis Derived Transcript (3 LIM Domains) (TES))

Andere Bezeichnung: TES

Hintergrund: Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.
Alias Symbols: DKFZp586B2022, MGC1146, TESS, TESS-2
Protein Interaction Partner: SUMO2, VPS25, RPRD1B, OSGEP, NAGK, HNRNPUL1, EPRS, EVL, SOCS3, SPTAN1, THADA, AHCYL1, SSSCA1, ZPR1, IGBP1, ELAVL1, UBC, ARAP1, Cep350, ENAH, SPOCK2, ACTL7A, TES, ZYX, VASP, GRIPAP1, TLN1, ACTN1, RAB8B, ACTA1, GRIP1,
Protein Size: 421

Molekulargewicht: 47 kDa

Gen-ID: 26136

NCBI Accession: NM_015641, NP_056456

UniProt: Q9UGI8