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CD33 Antikörper (N-Term)

CD33 Reaktivität: Human, Rind (Kuh), Pferd WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2789356
  • Target Alle CD33 Antikörper anzeigen
    CD33
    Bindungsspezifität
    • 16
    • 16
    • 13
    • 9
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 165
    • 35
    • 15
    • 13
    • 7
    • 6
    • 2
    Human, Rind (Kuh), Pferd
    Wirt
    • 92
    • 79
    Kaninchen
    Klonalität
    • 89
    • 81
    • 1
    Polyklonal
    Konjugat
    • 56
    • 16
    • 13
    • 12
    • 10
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD33 Antikörper ist unkonjugiert
    Applikation
    • 107
    • 99
    • 40
    • 30
    • 26
    • 26
    • 22
    • 22
    • 16
    • 13
    • 9
    • 9
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    HPIPYYDKNS PVHGYWFREG AIISRDSPVA TNKLDQEVQE ETQGRFRLLG
    Homologie
    Cow: 79%, Horse: 79%, Human: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CD33. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Top Product
    Discover our top product CD33 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 364 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CD33
    Andere Bezeichnung
    CD33 (CD33 Produkte)
    Synonyme
    SIGLEC-3 antikoerper, SIGLEC3 antikoerper, p67 antikoerper, Siglec-3 antikoerper, gp67 antikoerper, CD33 molecule antikoerper, CD33 antigen antikoerper, CD33 antikoerper, Cd33 antikoerper
    Hintergrund
    CD33 is a putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. CD33 preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, CD33 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33 induces apoptosis in acute myeloid leukemia (in vitro).
    Alias Symbols: FLJ00391, SIGLEC-3, SIGLEC3, p67
    Protein Interaction Partner: KRT40, KRT31, HERC3, UBC, CBL, SRC, PTPN6, PTPN11,
    Protein Size: 364
    Molekulargewicht
    38 kDa
    Gen-ID
    945
    NCBI Accession
    NM_001772, NP_001763
    UniProt
    P20138
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