CD33 Antikörper (N-Term)
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- Target Alle CD33 Antikörper anzeigen
- CD33
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Rind (Kuh), Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CD33 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- HPIPYYDKNS PVHGYWFREG AIISRDSPVA TNKLDQEVQE ETQGRFRLLG
- Homologie
- Cow: 79%, Horse: 79%, Human: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CD33. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product CD33 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 364 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CD33
- Andere Bezeichnung
- CD33 (CD33 Produkte)
- Synonyme
- SIGLEC-3 antikoerper, SIGLEC3 antikoerper, p67 antikoerper, Siglec-3 antikoerper, gp67 antikoerper, CD33 molecule antikoerper, CD33 antigen antikoerper, CD33 antikoerper, Cd33 antikoerper
- Hintergrund
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CD33 is a putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. CD33 preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, CD33 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33 induces apoptosis in acute myeloid leukemia (in vitro).
Alias Symbols: FLJ00391, SIGLEC-3, SIGLEC3, p67
Protein Interaction Partner: KRT40, KRT31, HERC3, UBC, CBL, SRC, PTPN6, PTPN11,
Protein Size: 364 - Molekulargewicht
- 38 kDa
- Gen-ID
- 945
- NCBI Accession
- NM_001772, NP_001763
- UniProt
- P20138
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