CD86 Antikörper (C-Term)

Produktnummer ABIN2789334

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CD86 in WB. Es zeigt Reaktivität gegenüber Proben von Human und Schwein.

Kurzübersicht für CD86 Antikörper (C-Term) (ABIN2789334)

Target: CD86

Reaktivität: Human, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD86 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD86 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: CD86 Antibody - C-terminal region

Sequenz: WKKKKRPRNS YKCGTNTMER EESEQTKKRE KIHIPERSDE AQRVFKSSKT

Homologie: Human: 100%, Pig: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against CD86. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63007-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CD86

Target: CD86

Andere Bezeichnung: CD86

Hintergrund:

Background Information: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

Gene Name: CD86 Molecule

Alternative Symbols: B70, B7-2, B7.2, LAB72, CD28LG2

Protein Name: T-lymphocyte activation antigen CD86 Ensembl ENSP00000420230

Molekulargewicht: 23kDa

Gen-ID: 942

NCBI Accession: NP_787058

UniProt: E9PC27

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation