MTMR6 Antikörper (C-Term)

Produktnummer ABIN2789053

Produktdetails anti-MTMR6 Antikörper

Target: MTMR6 (Myotubularin Related Protein 6 (MTMR6))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Meerschweinchen, Pferd, Kaninchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MTMR6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KDLESKIKQR KNKQTDGILT KELLHSVHPE SPNLKTSLCF KEQTLLPVND

Homologie: Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Rabbit: 86%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against MTMR6. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 621 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MTMR6

Target: MTMR6 (Myotubularin Related Protein 6 (MTMR6))

Andere Bezeichnung: MTMR6 (MTMR6 Produkte)

Synonyme: 4022440C11Rik antikoerper, AI428804 antikoerper, AU041072 antikoerper, zgc:55289 antikoerper, wu:fi04a11 antikoerper, si:dkey-286f3.1 antikoerper, zgc:56405 antikoerper, myotubularin related protein 6 antikoerper, myotubularin related protein 8 antikoerper, MTMR6 antikoerper, Mtmr6 antikoerper, mtmr6 antikoerper, mtmr8 antikoerper

Hintergrund: MTMR6 phosphatase that acts on lipids with a phosphoinositol headgroup. It acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol-3 phosphatase. It negatively regulates proliferation of reactivated CD4+ T-cells.
Alias Symbols: -
Protein Interaction Partner: MTMR9, AMOTL2, MTUS2, NMI, TRIM27, UBC, RARG, UBD, ELAVL1,
Protein Size: 621

Molekulargewicht: 68 kDa

Gen-ID: 9107

NCBI Accession: NM_004685, NP_004676

UniProt: Q9Y217

Pathways: Inositol Metabolic Process