MTMR6 Antikörper (C-Term)
Kurzübersicht für MTMR6 Antikörper (C-Term) (ABIN2789053)
Target
Alle MTMR6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- KDLESKIKQR KNKQTDGILT KELLHSVHPE SPNLKTSLCF KEQTLLPVND
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Homologie
- Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Rabbit: 86%, Rat: 79%
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Produktmerkmale
- This is a rabbit polyclonal antibody against MTMR6. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 621 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MTMR6 (Myotubularin Related Protein 6 (MTMR6))
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Andere Bezeichnung
- MTMR6
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Hintergrund
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MTMR6 phosphatase that acts on lipids with a phosphoinositol headgroup. It acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol-3 phosphatase. It negatively regulates proliferation of reactivated CD4+ T-cells.
Alias Symbols: -
Protein Interaction Partner: MTMR9, AMOTL2, MTUS2, NMI, TRIM27, UBC, RARG, UBD, ELAVL1,
Protein Size: 621 -
Molekulargewicht
- 68 kDa
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Gen-ID
- 9107
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NCBI Accession
- NM_004685, NP_004676
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UniProt
- Q9Y217
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Pathways
- Inositol Metabolic Process
Target
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