EIF3K Antikörper (N-Term)
Kurzübersicht für EIF3K Antikörper (N-Term) (ABIN2789047)
Target
Alle EIF3K Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- QILLKALTNL PHTDFTLCKC MIDQAHQEER PIRQILYLGD LLETCHFQAF
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against Eif3k. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 218 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- EIF3K (Eukaryotic Translation Initiation Factor 3 Subunit K (EIF3K))
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Andere Bezeichnung
- Eif3k
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Hintergrund
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Eif3k is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Alias Symbols: 1200009C21Rik, Eif3s12
Protein Interaction Partner: Eed, Plcb1,
Protein Size: 218 -
Molekulargewicht
- 25 kDa
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Gen-ID
- 73830
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NCBI Accession
- NM_028659, NP_082935
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UniProt
- Q9DBZ5
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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