EIF3K Antikörper (C-Term)

Produktnummer ABIN952051

Produktdetails anti-EIF3K Antikörper

Target: EIF3K (Eukaryotic Translation Initiation Factor 3 Subunit K (EIF3K))

Bindungsspezifität: AA 175-204, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF3K Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to EIF3K.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 175-204 amino acids from the C-terminal region of human EIF3K

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-EIF3K Antikörper (ABIN952051)

López-González, Schlüter, Aso, Garcia-Esparcia, Ansoleaga, LLorens, Carmona, Moreno, Fuso, Portero-Otin, Pamplona, Pujol, Ferrer: "Neuroinflammatory signals in Alzheimer disease and APP/PS1 transgenic mice: correlations with plaques, tangles, and oligomeric species." in: Journal of neuropathology and experimental neurology, Vol. 74, Issue 4, pp. 319-44, (2015) (PubMed).

Zhou, Sandercock, Fraser, Ridlova, Stephens, Schenauer, Yokoi-Fong, Barsky, Leary, Hershey, Doudna, Robinson: "Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 47, pp. 18139-44, (2008) (PubMed).

Lin, Chen, Lin, Wang, Inoko, Inagaki, Wu, Chen: "eIF3k regulates apoptosis in epithelial cells by releasing caspase 3 from keratin-containing inclusions." in: Journal of cell science, Vol. 121, Issue Pt 14, pp. 2382-93, (2008) (PubMed).

Damoc, Fraser, Zhou, Videler, Mayeur, Hershey, Doudna, Robinson, Leary: "Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 7, pp. 1135-46, (2007) (PubMed).

Masutani, Sonenberg, Yokoyama, Imataka: "Reconstitution reveals the functional core of mammalian eIF3." in: The EMBO journal, Vol. 26, Issue 14, pp. 3373-83, (2007) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Schweizer, Bowden, Coulombe, Langbein, Lane, Magin, Maltais, Omary, Parry, Rogers, Wright: "New consensus nomenclature for mammalian keratins." in: The Journal of cell biology, Vol. 174, Issue 2, pp. 169-74, (2006) (PubMed).

Details zu EIF3K

Target: EIF3K (Eukaryotic Translation Initiation Factor 3 Subunit K (EIF3K))

Andere Bezeichnung: EIF3K / EIF3S12 (EIF3K Produkte)

Synonyme: eif3s12 antikoerper, EIF3S12 antikoerper, ACYPI000023 antikoerper, eIF3k antikoerper, EIF3-p28 antikoerper, HSPC029 antikoerper, M9 antikoerper, MSTP001 antikoerper, PLAC-24 antikoerper, PLAC24 antikoerper, PRO1474 antikoerper, PTD001 antikoerper, 1200009C21Rik antikoerper, Eif3s12 antikoerper, zgc:110726 antikoerper, eukaryotic translation initiation factor 3 subunit K L homeolog antikoerper, eukaryotic translation initiation factor 3 subunit K antikoerper, eukaryotic translation initiation factor 3, subunit K antikoerper, eukaryotic translation initiation factor 3 subunit k antikoerper, Eukaryotic translation initiation factor 3 subunit K antikoerper, eif3k.L antikoerper, EIF3K antikoerper, eif3k antikoerper, ANI_1_1610144 antikoerper, AOR_1_2266174 antikoerper, Tsp_00068 antikoerper, Tsp_13184 antikoerper, Eif3k antikoerper, LOC733122 antikoerper, eif-3.K antikoerper

Hintergrund: The 700-kD eukaryotic translation initiation factor-3 (eIF3) is the largest eIF and contains at least 12 subunits, including EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and promoting formation of the 40S preinitiation complex (Mayeur et al., 2003 [PubMed 14519125]).Synonyms: Eukaryotic translation initiation factor 3 subunit 12, Eukaryotic translation initiation factor 3 subunit K, Muscle-specific gene M9 protein, PLAC-24, eIF-3 p25, eIF-3 p28

Molekulargewicht: 25060 Da

Gen-ID: 27335

NCBI Accession: NP_037366

Pathways: Ribonucleoprotein Complex Subunit Organization