Cullin 4B Antikörper (C-Term)
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- Target Alle Cullin 4B (CUL4B) Antikörper anzeigen
- Cullin 4B (CUL4B)
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Ziege
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Cullin 4B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- IQMKETVEEQ ASTTERVFQD RQYQIDAAIV RIMKMRKTLS HNLLVSEVYN
- Homologie
- Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against Cul4b. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product CUL4B Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 970 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Cullin 4B (CUL4B)
- Andere Bezeichnung
- Cul4b (CUL4B Produkte)
- Hintergrund
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Cul4b is a core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit. CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.
Alias Symbols: 2700050M05Rik, AA409770, KIAA0695, mKIAA0695, CUL-4B
Protein Interaction Partner: Nedd8, Eed, Pou5f1,
Protein Size: 970 - Molekulargewicht
- 111 kDa
- Gen-ID
- 72584
- NCBI Accession
- NM_001110142, NP_001103612
- UniProt
- A2A432
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