Cullin 4B Antikörper (C-Term)
Kurzübersicht für Cullin 4B Antikörper (C-Term) (ABIN2789003)
Target
Alle Cullin 4B (CUL4B) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- IQMKETVEEQ ASTTERVFQD RQYQIDAAIV RIMKMRKTLS HNLLVSEVYN
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Homologie
- Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against Cul4b. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 970 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Cullin 4B (CUL4B)
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Andere Bezeichnung
- Cul4b
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Hintergrund
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Cul4b is a core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit. CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.
Alias Symbols: 2700050M05Rik, AA409770, KIAA0695, mKIAA0695, CUL-4B
Protein Interaction Partner: Nedd8, Eed, Pou5f1,
Protein Size: 970 -
Molekulargewicht
- 111 kDa
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Gen-ID
- 72584
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NCBI Accession
- NM_001110142, NP_001103612
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UniProt
- A2A432
Target
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