Cullin 4B Antikörper (C-Term)

Produktnummer ABIN2789003

Dieser Anti-Cullin 4B-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von Cullin 4B in WB. Geeignet für Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen und Ziege.

Kurzübersicht für Cullin 4B Antikörper (C-Term) (ABIN2789003)

Target: Cullin 4B (CUL4B)

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cullin 4B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Cullin 4B Antikörper

Bindungsspezifität: C-Term

Sequenz: IQMKETVEEQ ASTTERVFQD RQYQIDAAIV RIMKMRKTLS HNLLVSEVYN

Homologie: Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Cul4b. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 970 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Cullin 4B

Target: Cullin 4B (CUL4B)

Andere Bezeichnung: Cul4b

Hintergrund: Cul4b is a core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit. CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.
Alias Symbols: 2700050M05Rik, AA409770, KIAA0695, mKIAA0695, CUL-4B
Protein Interaction Partner: Nedd8, Eed, Pou5f1,
Protein Size: 970

Molekulargewicht: 111 kDa

Gen-ID: 72584

NCBI Accession: NM_001110142, NP_001103612

UniProt: A2A432