HMGN3 Antikörper (Middle Region)

Produktnummer ABIN2788959

Produktdetails anti-HMGN3 Antikörper

Target: HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Pferd, Hund, Meerschweinchen, Kaninchen, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMGN3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SKPRKTSAKK EPGTKISRGA KGKKEEKQEA GEEGTAPSAN GDTKVEEAQR

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against Hmgn3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Hmgn3

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HMGN3

Target: HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))

Andere Bezeichnung: Hmgn3 (HMGN3 Produkte)

Synonyme: Trip7 antikoerper, PNAS-25 antikoerper, TRIP7 antikoerper, 1110002A15Rik antikoerper, 6330514M13Rik antikoerper, BB071015 antikoerper, high mobility group nucleosomal binding domain 3 L homeolog antikoerper, high mobility group nucleosomal binding domain 3 antikoerper, hmgn3.L antikoerper, HMGN3 antikoerper, Hmgn3 antikoerper

Hintergrund: Hmgn3 binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. It affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion, regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors and regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. It may play a role in ocular development and astrocyte function.
Alias Symbols: 1110002A15Rik, 6330514M13Rik, BB071015, TRIP7
Protein Size: 99

Molekulargewicht: 11 kDa

Gen-ID: 94353

NCBI Accession: NM_026122, NP_080398

UniProt: Q9DCB1