HMGN3 Antikörper (Middle Region)

Produktnummer ABIN2788959

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HMGN3 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Pferd, Hund, Meerschweinchen, Kaninchen, Rind (Kuh) und Schwein.

Kurzübersicht für HMGN3 Antikörper (Middle Region) (ABIN2788959)

Target: HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))

Reaktivität: Human, Maus, Ratte, Pferd, Hund, Meerschweinchen, Kaninchen, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMGN3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HMGN3 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: Hmgn3 Antibody - middle region

Sequenz: SKPRKTSAKK EPGTKISRGA KGKKEEKQEA GEEGTAPSAN GDTKVEEAQR

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against Hmgn3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Hmgn3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61954-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu HMGN3

Target: HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))

Andere Bezeichnung: Hmgn3

Hintergrund:

Background Information: Hmgn3 binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. It affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion, regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors and regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. It may play a role in ocular development and astrocyte function.

Gene Name: high mobility group nucleosomal binding domain 3

Alternative Symbols: TR, HMGN, TRIP7, BB071015, 1110002A15Rik, 6330514M13Rik

Protein Name: High mobility group nucleosome-binding domain-containing protein 3

Molekulargewicht: 11kDa

Gen-ID: 94353

NCBI Accession: NP_080398

UniProt: Q9DCB1