Trip7 antikoerper, PNAS-25 antikoerper, TRIP7 antikoerper, 1110002A15Rik antikoerper, 6330514M13Rik antikoerper, BB071015 antikoerper, high mobility group nucleosomal binding domain 3 L homeolog antikoerper, high mobility group nucleosomal binding domain 3 antikoerper, hmgn3.L antikoerper, HMGN3 antikoerper, Hmgn3 antikoerper
Hintergrund
Hmgn3 binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. It affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion, regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors and regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. It may play a role in ocular development and astrocyte function. Alias Symbols: 1110002A15Rik, 6330514M13Rik, BB071015, TRIP7 Protein Size: 99