PDGFC Antikörper (N-Term)

Produktnummer ABIN2788903

Produktdetails anti-PDGFC Antikörper

Target: PDGFC (Platelet-Derived Growth Factor C (PDGFC))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDGFC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MLLLGLLLLT SALAGQRTGT RAESNLSSKL QLSSDKEQNG VQDPRHERVV

Homologie: Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against Pdgfc. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Pdgfc

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PDGFC

Target: PDGFC (Platelet-Derived Growth Factor C (PDGFC))

Andere Bezeichnung: Pdgfc (PDGFC Produkte)

Synonyme: SCDGF antikoerper, FALLOTEIN antikoerper, 1110064L01Rik antikoerper, AI647969 antikoerper, PDGF-C antikoerper, platelet derived growth factor C antikoerper, platelet-derived growth factor, C polypeptide antikoerper, PDGFC antikoerper, Pdgfc antikoerper

Substanzklasse: Viral Protein

Hintergrund: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen and chemoattractant for cells of mesenchymal origin. Required for normal skeleton formation during embryonic development, especially for normal development of the craniofacial skeleton and for normal development of the palate. Required for normal skin morphogenesis during embryonic development. Plays an important role in wound healing, where it appears to be involved in three stages: inflammation, proliferation and remodeling. Plays an important role in angiogenesis and blood vessel development. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintenance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function.
Alias Symbols: 1110064L01Rik, AI647969, PDGF-C
Protein Size: 345

Molekulargewicht: 39 kDa

Gen-ID: 54635

NCBI Accession: NM_019971, NP_064355

UniProt: Q8CI19

Pathways: RTK Signalweg, Platelet-derived growth Factor Receptor Signaling