CDK11 Antikörper (Middle Region)

Produktnummer ABIN2788891

Der Kaninchen Polyklonal anti-CDK11 Antikörper (ABIN2788891) detektiert spezifisch CDK11 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Rind (Kuh), Schwein, Ratte, Hund, Pferd, Kaninchen, Saccharomyces cerevisiae und Zebrafisch (Danio rerio).

Kurzübersicht für CDK11 Antikörper (Middle Region) (ABIN2788891)

Target: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Reaktivität: Human, Maus, Rind (Kuh), Schwein, Ratte, Hund, Pferd, Kaninchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CDK11 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: CDK11B Antibody - middle region

Sequenz: REQEKELREQ EKELREQKEL REQEEQMQEQ EEKMWEQEEK MREQEEKMWR

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against LOC283685. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CDK11B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61760-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CDK11

Target: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Andere Bezeichnung: CDK11B

Hintergrund:

Background Information: This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants.

Gene Name: cyclin-dependent kinase 11B

Alternative Symbols: p58, PK58, CDK11, CLK-1, CDC2L1, PITSLREA, p58CLK-1, CDK11-p46, CDK11-p58, p58CDC2L1, CDK11-p110

Protein Name: cyclin-dependent kinase 11B

Molekulargewicht: 34kDa

Gen-ID: 984

NCBI Accession: NP_277022

UniProt: P21127

Pathways: Regulation of Lipid Metabolism by PPARalpha, M Phase