EIF5B Antikörper (Middle Region)
Kurzübersicht für EIF5B Antikörper (Middle Region) (ABIN2788862)
Target
Alle EIF5B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- EIF5B Antibody - middle region
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Sequenz
- SEGSEGDEED EKVSDEKDSG KTLDKKPSKE MSSDSEYDSD DDRTKEERAY
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Homologie
- Cow: 86%, Dog: 86%, Horse: 86%, Human: 100%, Pig: 93%, Rabbit: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against EIF5B. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61644-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- EIF5B (Eukaryotic Translation Initiation Factor 5B (EIF5B))
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Andere Bezeichnung
- EIF5B
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Hintergrund
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Background Information: Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately.
Gene Name: Eukaryotic translation initiation factor 5B
Alternative Symbols: IF2
Protein Name: Eukaryotic translation initiation factor 5B
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Molekulargewicht
- 139kDa
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Gen-ID
- 9669
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NCBI Accession
- NP_056988
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UniProt
- O60841
Target
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