PEX19 Antikörper (C-Term)

Produktnummer ABIN2788834

Der Kaninchen Polyklonal anti-PEX19 Antikörper (ABIN2788834) detektiert spezifisch PEX19 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd und Schwein.

Kurzübersicht für PEX19 Antikörper (C-Term) (ABIN2788834)

Target: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Reaktivität: Human, Ratte, Maus, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PEX19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PEX19 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: PEX19 Antibody - C-terminal region

Sequenz: AETPTDSETT QKARFEMVLD LMQQLQDLGH PPKELAGEMP PGLNFDLDAL

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PEX19. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61545-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PEX19

Target: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Andere Bezeichnung: PEX19

Hintergrund:

Background Information: This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.

Gene Name: Peroxisomal biogenesis factor 19

Alternative Symbols: PXF, HK33, PMP1, PMPI, PXMP1, PBD12A, D1S2223E

Protein Name: Peroxisomal biogenesis factor 19

Molekulargewicht: 33kDa

Gen-ID: 5824

NCBI Accession: NP_002848

UniProt: P40855