PEX19 Antikörper (C-Term)

Produktnummer ABIN2788834

Produktdetails anti-PEX19 Antikörper

Target: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PEX19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AETPTDSETT QKARFEMVLD LMQQLQDLGH PPKELAGEMP PGLNFDLDAL

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PEX19. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 299 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PEX19

Target: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Andere Bezeichnung: PEX19 (PEX19 Produkte)

Synonyme: BEST:GH03076 antikoerper, CG5325 antikoerper, DmelPex19 antikoerper, Dmel\\CG5325 antikoerper, D1S2223E antikoerper, HK33 antikoerper, PBD12A antikoerper, PMP1 antikoerper, PMPI antikoerper, PXF antikoerper, PXMP1 antikoerper, Pxf antikoerper, PxF antikoerper, Peroxin-19 antikoerper, Peroxin 19 antikoerper, Peroxisomal farnesylated protein antikoerper, peroxisomal biogenesis factor 19 antikoerper, Pex19 antikoerper, Bm1_19905 antikoerper, PEX19 antikoerper

Hintergrund: This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.
Alias Symbols: D1S2223E, FLJ55296, HK33, PMP1, PMPI, PXF, PXMP1
Protein Interaction Partner: FKBP7, IL23A, PEX3, UBC, PPIB, PTPLAD1, VCP, PXMP4, SLC25A17, PEX16, PEX11B, ABCD3, PMP22, EGFR, Cdkn2a, Pxmp2, TMEM54, MFSD5, PEX26, GSKIP, F11R, KIFAP3, OIP5, EIF1B, PEX11A, STK3, SRPK1, PEX14, PEX13, SMAD2, IRF3, CDC25A, NUDCD2, DSTN, NUBP2, HSPB1, PEX
Protein Size: 299

Molekulargewicht: 33 kDa

Gen-ID: 5824

NCBI Accession: NM_002857, NP_002848

UniProt: P40855