MUS81 Antikörper (C-Term)

Produktnummer ABIN2788792

Dieses Anti-MUS81-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MUS81 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund und Schwein.

Kurzübersicht für MUS81 Antikörper (C-Term) (ABIN2788792)

Target: MUS81 (MUS81 Endonuclease Homolog (MUS81))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MUS81 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MUS81 Antikörper

Bindungsspezifität: C-Term

Sequenz: GETRGGGHRP ELLRELQRLH VTHTVRKLHV GDFVWVAQET NPRDPANPGE

Homologie: Cow: 79%, Dog: 86%, Human: 100%, Mouse: 79%, Pig: 83%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against MUS81. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 551 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MUS81

Target: MUS81 (MUS81 Endonuclease Homolog (MUS81))

Andere Bezeichnung: MUS81

Hintergrund: MUS81 interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. It may be required in mitosis for the processing of stalled or collapsed replication forks.
Alias Symbols: FLJ21012, FLJ44872, SLX3
Protein Interaction Partner: SLX4, vpr, EME1, PLK1, FBXL5, SLX1A, WEE1, EME2, SUMO2, SLX1B, MUS81, CHEK2, TERT, TERF2,
Protein Size: 551

Molekulargewicht: 61 kDa

Gen-ID: 80198

NCBI Accession: NM_025128, NP_079404

UniProt: Q96NY9

Pathways: DNA Reparatur