RCC1 Antikörper (C-Term)

Produktnummer ABIN2788760

Produktdetails anti-RCC1 Antikörper

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Rind (Kuh), Hund, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RCC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AWGMGTNYQL GTGQDEDAWS PVEMMGKQLE NRVVLSVSSG GQHTVLLVKD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RCC1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 421 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RCC1

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Andere Bezeichnung: RCC1 (RCC1 Produkte)

Synonyme: Chc1 antikoerper, zgc:65796 antikoerper, zgc:77114 antikoerper, wu:fj77f08 antikoerper, rcc1 antikoerper, chc1-a antikoerper, BJ1 antikoerper, CG10480 antikoerper, CG18640 (Bj1) antikoerper, Dmel\\CG10480 antikoerper, RCC1 antikoerper, RanGEF antikoerper, Rcc1 antikoerper, dRCC1 antikoerper, inxs antikoerper, sdt antikoerper, xrcc1 antikoerper, chc1-b antikoerper, MGC115703 antikoerper, MGC132085 antikoerper, CHC1 antikoerper, RCC1-I antikoerper, SNHG3-RCC1 antikoerper, 4931417M11Rik antikoerper, AI326872 antikoerper, regulator of chromosome condensation 1 antikoerper, regulator of chromosome condensation 1 L homeolog antikoerper, Regulator of chromosome condensation 1 antikoerper, N terminal fragment of RCC1; similar to S. cerevisiae SRM1 (YGL097W) guanine nucleotide exchange factor for Gsp1 GTPase involved in assembly of nuclear pore complex; frameshifted antikoerper, regulator of chromosome condensation 1 S homeolog antikoerper, rcc1 antikoerper, RCC1 antikoerper, rcc1.L antikoerper, Rcc1 antikoerper, rcc1.S antikoerper

Hintergrund: RCC1 is a Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
Alias Symbols: CHC1, RCC1-I, SNHG3-RCC1
Protein Interaction Partner: UBC, SUMO2, SUMO1, NEDD8, MDM2, SUZ12, RNF2, PTMA, HDAC9, HMGA1, VCAM1, ITGA4, FN1, U2AF1, RANBP1, RAN, HNRNPM, HNRNPK, LUC7L3, SF3B6, NCSTN, ACIN1, RBM14, HDGF, SPRED1, FLAD1, WIZ, LRIF1, CSAD, SDF4, TRMT2A, DDAH2, FAF1, NUDT21, CCT7, TUBB3, CDK2AP2, KMT
Protein Size: 421

Molekulargewicht: 45 kDa

Gen-ID: 1104

NCBI Accession: NM_001269, NP_001260

UniProt: P18754

Pathways: Chromatin Binding, Protein targeting to Nucleus