CAMK2B Antikörper (Middle Region)

Produktnummer ABIN2788743

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CAMK2B in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen und Zebrafisch (Danio rerio).

Kurzübersicht für CAMK2B Antikörper (Middle Region) (ABIN2788743)

Target: CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CAMK2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CAMK2B Antikörper

Bindungsspezifität: Middle Region

Sequenz: SAKSLLNKKA DGVKPQTNST KNSAAATSPK GTLPPAALEP QTTVIHNPVD

Homologie: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CAMK2B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 517 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CAMK2B

Target: CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))

Andere Bezeichnung: CAMK2B

Hintergrund: The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene.
Alias Symbols: CAM2, CAMK2, CAMKB, MGC29528
Protein Interaction Partner: KRTAP10-11, KRTAP19-7, KRTAP19-5, FAM171A2, MGAT5B, CCM2L, TTC5, AP5B1, MRPL11, SEMA4G, SPRYD7, MED18, POP5, RBFOX2, ACOT7, RBPMS, MORF4L1, MAD2L2, RPL11, RAP2B, PHKB, CAMK2B, MVP, SMYD3, UBC, ATXN1, HSP90AA1, Rad23a, THRB, RXRG, YWHAB, CAMK2N2, CAMK2D, A
Protein Size: 517

Molekulargewicht: 57 kDa

Gen-ID: 816

NCBI Accession: NM_172080, NP_742077

UniProt: A4D2K5

Pathways: WNT Signalweg, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity