CAMK2B Antikörper (C-Term)

Produktnummer ABIN2788742

Der Kaninchen Polyklonal anti-CAMK2B Antikörper (ABIN2788742) detektiert spezifisch CAMK2B in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio) und Hund.

Kurzübersicht für CAMK2B Antikörper (C-Term) (ABIN2788742)

Target: CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CAMK2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CAMK2B Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: CAMK2B Antibody - C-terminal region

Sequenz: NPHVHVIGED AACIAYIRLT QYIDGQGRPR TSQSEETRVW HRRDGKWQNV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CAMK2B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CAMK2B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61268-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CAMK2B

Target: CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))

Andere Bezeichnung: CAMK2B

Hintergrund:

Targeted Subunit: beta

Background Information: The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene.

Gene Name: Calcium/calmodulin-dependent protein kinase II beta

Alternative Symbols: CAM2, CAMK2, CAMKB, MRD54, CaMKIIbeta

Protein Name: Calcium/calmodulin-dependent protein kinase IIB isoform 2 variant EMBL BAD96423.1

Molekulargewicht: 60kDa

Gen-ID: 816

NCBI Accession: NP_742075

UniProt: Q53H78

Pathways: WNT Signalweg, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity