CAMK2B Antikörper (C-Term)
Kurzübersicht für CAMK2B Antikörper (C-Term) (ABIN2788742)
Target
Alle CAMK2B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- NPHVHVIGED AACIAYIRLT QYIDGQGRPR TSQSEETRVW HRRDGKWQNV
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CAMK2B. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human CAMK2B
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 542 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))
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Andere Bezeichnung
- CAMK2B
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Hintergrund
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The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene.
Alias Symbols: CAM2, CAMK2, CAMKB, MGC29528
Protein Interaction Partner: KRTAP10-11, KRTAP19-7, KRTAP19-5, FAM171A2, MGAT5B, CCM2L, TTC5, AP5B1, MRPL11, SEMA4G, SPRYD7, MED18, POP5, RBFOX2, ACOT7, RBPMS, MORF4L1, MAD2L2, RPL11, RAP2B, PHKB, CAMK2B, MVP, SMYD3, UBC, ATXN1, HSP90AA1, Rad23a, THRB, RXRG, YWHAB, CAMK2N2, CAMK2D, A
Protein Size: 542 -
Molekulargewicht
- 60 kDa
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Gen-ID
- 816
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NCBI Accession
- NM_172078, NP_742075
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UniProt
- Q53H78
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Pathways
- WNT Signalweg, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
Target
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