UNG Antikörper (C-Term)

Produktnummer ABIN2788718

Der Kaninchen Polyklonal Anti-UNG-Antikörper wurde für WB validiert. Er ist geeignet, UNG in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Kaninchen und Saccharomyces cerevisiae zu detektieren.

Kurzübersicht für UNG Antikörper (C-Term) (ABIN2788718)

Target: UNG (Uracil-DNA Glycosylase (UNG))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UNG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-UNG Antikörper

Bindungsspezifität: C-Term

Sequenz: GWAKQGVLLL NAVLTVRAHQ ANSHKERGWE QFTDAVVSWL NQNSNGLVFL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%, Yeast: 79%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against UNG. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 313 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu UNG

Target: UNG (Uracil-DNA Glycosylase (UNG))

Andere Bezeichnung: UNG

Hintergrund: This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases.
Alias Symbols: DGU, DKFZp781L1143, HIGM4, UDG, UNG1, UNG15, UNG2
Protein Interaction Partner: RPA3, RPA2, RPA1, vpr, SEZ6L2, CAPN11, UBC, SMUG1, UBE2E2, THOP1, APP, POLB, HSPB1, VPRBP, DDB1, PCNA, PPM1D,
Protein Size: 313

Molekulargewicht: 34 kDa

Gen-ID: 7374

NCBI Accession: NM_080911, NP_550433

UniProt: P13051

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response