IL2 Receptor beta Antikörper (C-Term)
-
- Target Alle IL2 Receptor beta (IL2RB) Antikörper anzeigen
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
-
Bindungsspezifität
- C-Term
-
Reaktivität
- Human, Ratte, Saccharomyces cerevisiae
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser IL2 Receptor beta Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- QGYFFFHLPD ALEIEACQVY FTYDPYSEED PDEGVAGAPT GSSPQPLQPL
- Homologie
- Human: 100%, Rat: 77%, Yeast: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against IL2RB. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product IL2RB Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 551 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
- Andere Bezeichnung
- IL2RB (IL2RB Produkte)
- Synonyme
- IL2RB antikoerper, il-2rb antikoerper, CD122 antikoerper, IL15RB antikoerper, P70-75 antikoerper, IL2RBC antikoerper, IL-15Rbeta antikoerper, IL15Rbeta antikoerper, Il-2/15Rbeta antikoerper, Il-2Rbeta antikoerper, p70 antikoerper, interleukin 2 receptor subunit beta antikoerper, interleukin-2 receptor subunit beta antikoerper, interleukin 2 receptor, beta antikoerper, interleukin 2 receptor, beta chain antikoerper, IL2RB antikoerper, LOC510185 antikoerper, il2rb antikoerper, Il2rb antikoerper
- Hintergrund
-
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.
Alias Symbols: CD122, P70-75, IL15RB
Protein Interaction Partner: ECM1, JAK1, SOCS3, LCK, NEDD4, HGS, UBC, EIF3B, STAT5B, SOCS1, CISH, STAT5A, IL15RA, SHC1, STAT1, IL15, SHB, JAK3, SYK, IL2RG, GNB2L1, PTPN6, PIK3R1, LYN, RAF1, IL2RA, IL2, FYN, GRB2, STAT3, JAK2,
Protein Size: 551 - Molekulargewicht
- 58 kDa
- Gen-ID
- 3560
- NCBI Accession
- NM_000878, NP_000869
- UniProt
- P14784
- Pathways
- JAK-STAT Signalweg, Growth Factor Binding
-