IL2 Receptor beta Antikörper (C-Term)

Produktnummer ABIN2788713

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch IL2 Receptor beta in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Saccharomyces cerevisiae.

Kurzübersicht für IL2 Receptor beta Antikörper (C-Term) (ABIN2788713)

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Reaktivität: Human, Ratte, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL2 Receptor beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IL2 Receptor beta Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: IL2RB Antibody - C-terminal region

Sequenz: QGYFFFHLPD ALEIEACQVY FTYDPYSEED PDEGVAGAPT GSSPQPLQPL

Homologie: Human: 100%, Rat: 77%, Yeast: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against IL2RB. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61193-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu IL2 Receptor beta

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Andere Bezeichnung: IL2RB

Hintergrund:

Targeted Subunit: beta

Background Information: The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.

Gene Name: Interleukin 2 receptor, beta

Alternative Symbols: CD122, IMD63, IL15RB, P70-75

Protein Name: Interleukin-2 receptor subunit beta

Molekulargewicht: 58kDa

Gen-ID: 3560

NCBI Accession: NP_000869

UniProt: P14784

Pathways: JAK-STAT Signalweg, Growth Factor Binding