IL2 Receptor beta Antikörper (C-Term)

Produktnummer ABIN2788713

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IL2 Receptor beta in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte und Saccharomyces cerevisiae.

Kurzübersicht für IL2 Receptor beta Antikörper (C-Term) (ABIN2788713)

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Reaktivität: Human, Ratte, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL2 Receptor beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IL2 Receptor beta Antikörper

Bindungsspezifität: C-Term

Sequenz: QGYFFFHLPD ALEIEACQVY FTYDPYSEED PDEGVAGAPT GSSPQPLQPL

Homologie: Human: 100%, Rat: 77%, Yeast: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against IL2RB. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 551 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IL2 Receptor beta

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Andere Bezeichnung: IL2RB

Hintergrund: The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.
Alias Symbols: CD122, P70-75, IL15RB
Protein Interaction Partner: ECM1, JAK1, SOCS3, LCK, NEDD4, HGS, UBC, EIF3B, STAT5B, SOCS1, CISH, STAT5A, IL15RA, SHC1, STAT1, IL15, SHB, JAK3, SYK, IL2RG, GNB2L1, PTPN6, PIK3R1, LYN, RAF1, IL2RA, IL2, FYN, GRB2, STAT3, JAK2,
Protein Size: 551

Molekulargewicht: 58 kDa

Gen-ID: 3560

NCBI Accession: NM_000878, NP_000869

UniProt: P14784

Pathways: JAK-STAT Signalweg, Growth Factor Binding