PFKM Antikörper (C-Term)

Produktnummer ABIN2788704

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PFKM in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Kaninchen, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio) und Rind (Kuh).

Kurzübersicht für PFKM Antikörper (C-Term) (ABIN2788704)

Target: PFKM (phosphofructokinase, Muscle (PFKM))

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PFKM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PFKM Antikörper

Bindungsspezifität: C-Term

Sequenz: RALVFQPVAE LKDQTDFEHR IPKEQWWLKL RPILKILAKY EIDLDTSDHA

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PFKM. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PFKM

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 780 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PFKM

Target: PFKM (phosphofructokinase, Muscle (PFKM))

Andere Bezeichnung: PFKM

Hintergrund: Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
Alias Symbols: GSD7, MGC8699, PFK-1, PFK1, PFKA, PFKX
Protein Interaction Partner: UBC, SIAH1, PFKM, SUMO2, EGFR, DCP2, DCP1A, TUBB2A, PFKP, PCBP1, UBTD1, FBXO6, LSM7, PFKL, NDUFB2, Hoxa1, CUL3, MAPK3, PCNA, SUMO1, ATP6V0A4, FHL2, DYNLL1, CAV3, NOS1, HGS,
Protein Size: 780

Molekulargewicht: 85 kDa

Gen-ID: 5213

NCBI Accession: NM_000289, NP_000280

UniProt: P08237

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Warburg Effekt