Clusterin Antikörper (C-Term)

Produktnummer ABIN2788692

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Clusterin in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Kaninchen, Pferd und Meerschweinchen.

Kurzübersicht für Clusterin Antikörper (C-Term) (ABIN2788692)

Target: Clusterin (CLU)

Reaktivität: Human, Ratte, Maus, Kaninchen, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Clusterin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Clusterin Antikörper

Bindungsspezifität: C-Term

Sequenz: CREILSVDCS TNNPSQAKLR RELDESLQVA ERLTRKYNEL LKSYQWKMLN

Homologie: Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 91%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against CLU. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLU

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 501 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Clusterin

Target: Clusterin (CLU)

Andere Bezeichnung: CLU

Hintergrund: The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.
Alias Symbols: AAG4, APOJ, CLI, KUB1, MGC24903, SGP-2, SGP2, SP-40, APO-J, NA1/NA2
Protein Interaction Partner: HYOU1, HSP90B1, HSPA5, BAX, TUFM, NUCB2, HSPA1L, TUBB6, MDM2, FOS, CDK19, APOA1, KEAP1, POLR1C, RPL23, KLF11, BAG6, RBBP8, MAPK9, PDIA3, CYP2E1, BCL2L1, TSC22D4, MDC1, LIG4, PAXIP1, CLUAP1, IL24, PRNP, PON1, HSPD1, APP, FBXO6, LYZ, LRP2, HBA1, XRCC6, ELN,
Protein Size: 501

Molekulargewicht: 58 kDa

Gen-ID: 1191

NCBI Accession: NM_001831, NP_001822

UniProt: P10909

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling