GABBR2 Antikörper (C-Term)

Produktnummer ABIN2788680

Produktdetails anti-GABBR2 Antikörper

Target: GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABBR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QFTQNQKKED SKTSTSVTSV NQASTSRLEG LQSENHRLRM KITELDKDLE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GABBR2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GABBR2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 941 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GABBR2

Target: GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))

Andere Bezeichnung: GABBR2 (GABBR2 Produkte)

Synonyme: Gpr51 antikoerper, GABABR2 antikoerper, GPR51 antikoerper, GPRC3B antikoerper, HG20 antikoerper, HRIHFB2099 antikoerper, Gb2 antikoerper, Gm425 antikoerper, GABA(B)R2 antikoerper, si:dkey-190l1.2 antikoerper, gamma-aminobutyric acid type B receptor subunit 2 antikoerper, gamma-aminobutyric acid (GABA) B receptor, 2 antikoerper, gamma-aminobutyric acid (GABA) B receptor, 2 S homeolog antikoerper, GABBR2 antikoerper, LOC100448699 antikoerper, gabbr2 antikoerper, Gabbr2 antikoerper, gabbr2.S antikoerper

Hintergrund: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.
Alias Symbols: FLJ36928, GABABR2, GPR51, GPRC3B, HG20, HRIHFB2099
Protein Interaction Partner: KCTD12, GLP1R, Dlg4, GRASP, ATF4, ATF5, GABBR1, SH3GL3, NSF, HTR1A,
Protein Size: 941

Molekulargewicht: 106 kDa

Gen-ID: 9568

NCBI Accession: NM_005458, NP_005449

UniProt: O75899

Pathways: cAMP Metabolic Process