SYK Antikörper (Middle Region)

Produktnummer ABIN2788676

Der Kaninchen Polyklonal Anti-SYK-Antikörper wurde für WB validiert. Er ist geeignet, SYK in Proben von Human, Schwein und Pferd zu detektieren.

Kurzübersicht für SYK Antikörper (Middle Region) (ABIN2788676)

Target: SYK (Spleen tyrosine Kinase (SYK))

Reaktivität: Human, Schwein, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SYK Antikörper

Bindungsspezifität: Middle Region

Sequenz: RIKSYSFPKP GHRKSSPAQG NRQESTVSFN PYEPELAPWA ADKGPQREAL

Homologie: Horse: 85%, Human: 100%, Pig: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SYK. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 635 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SYK

Target: SYK (Spleen tyrosine Kinase (SYK))

Andere Bezeichnung: SYK

Hintergrund: This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DKFZp313N1010, FLJ25043, FLJ37489, p72-Syk
Protein Interaction Partner: SH2D2A, TRAF6, STAT3, USP25, IL17RA, TRAF3IP2, PTPRO, UBC, FCGR3A, TICAM1, TLR9, TBK1, TRAF3, TLR4, TLR3, MAP3K7, MYD88, SRC, SYK, UBASH3B, VCAM1, ITGA4, ERBB4, ERBB3, ERBB2, EGFR, APP, SH3BP2, MAPT, TUBB, VAV2, VAV1, PIK3CG, BLNK, CBL, BTK, PIK3R1, TRAIP
Protein Size: 635

Molekulargewicht: 72 kDa

Gen-ID: 6850

NCBI Accession: NM_003177, NP_003168

UniProt: P43405

Pathways: Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling