Factor XI Antikörper (C-Term)

Produktnummer ABIN2788664

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Factor XI in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für Factor XI Antikörper (C-Term) (ABIN2788664)

Target: Factor XI (F11) (Coagulation Factor XI (F11))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Factor XI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Factor XI Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: F11 Antibody - C-terminal region

Sequenz: RHLCGGSIIG NQWILTAAHC FYGVESPKIL RVYSGILNQS EIKEDTSFFG

Homologie: Cow: 100%, Dog: 79%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 82%, Rabbit: 93%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against F11. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human F11

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61075-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Factor XI

Target: Factor XI (F11) (Coagulation Factor XI (F11))

Andere Bezeichnung: F11

Hintergrund:

Background Information: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.

Gene Name: Coagulation factor XI

Alternative Symbols: FXI, PTA

Protein Name: Coagulation factor XI

Molekulargewicht: 70kDa

Gen-ID: 2160

NCBI Accession: NP_000119

UniProt: P03951