BID Antikörper (C-Term)

Produktnummer ABIN2788659

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch BID in WB und IF. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Hund und Pferd.

Kurzübersicht für BID Antikörper (C-Term) (ABIN2788659)

Target: BID (BH3 Interacting Domain Death Agonist (BID))

Reaktivität: Human, Ratte, Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BID Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-BID Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: BID Antibody - C-terminal region

Sequenz: LRNTSRSEED RNRDLATALE QLLQAYPRDM EKEKTMLVLA LLLAKKVASH

Homologie: Dog: 86%, Horse: 86%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against BID. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61037-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu BID

Target: BID (BH3 Interacting Domain Death Agonist (BID))

Andere Bezeichnung: BID

Hintergrund:

Background Information: This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

Gene Name: BH3 interacting domain death agonist

Alternative Symbols: FP497

Protein Name: cDNA FLJ37476 fis, clone BRAWH2012827, highly similar to Homo sapiens BH3 interacting domain death agonist (BID), transcript variant 1, mRNA EMBL BAG52933.1

Molekulargewicht: 27kDa

Gen-ID: 637

NCBI Accession: NP_932070

UniProt: B3KT21

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity