LHCGR Antikörper (C-Term)

Produktnummer ABIN2788657

Der Kaninchen Polyklonal anti-LHCGR Antikörper (ABIN2788657) detektiert spezifisch LHCGR in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Schwein und Kaninchen.

Kurzübersicht für LHCGR Antikörper (C-Term) (ABIN2788657)

Target: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LHCGR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LHCGR Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: LHCGR Antibody - C-terminal region

Sequenz: LLLSKFGCCK RRAELYRRKD FSAYTSNCKN GFTGSNKPSQ STLKLSTLHC

Homologie: Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Pig: 93%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against LHCGR. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human LHCGR

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61025-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu LHCGR

Target: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Andere Bezeichnung: LHCGR

Hintergrund:

Background Information: This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia.

Gene Name: luteinizing hormone/choriogonadotropin receptor

Alternative Symbols: HHG, LHR, LCGR, LGR2, ULG5, LHRHR, LSH-R, LH/CGR, LH/CG-R

Protein Name: lutropin-choriogonadotropic hormone receptor

Molekulargewicht: 69kDa

Gen-ID: 3973

UniProt: P22888

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling