FLT1 Antikörper (C-Term)

Produktnummer ABIN2788655

Der Kaninchen Polyklonal anti-FLT1 Antikörper (ABIN2788655) detektiert spezifisch FLT1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh), Kaninchen und Ziege.

Kurzübersicht für FLT1 Antikörper (C-Term) (ABIN2788655)

Target: FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Reaktivität: Human, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh), Kaninchen, Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FLT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FLT1 Antikörper

Bindungsspezifität: C-Term

Sequenz: DLRVTSKSKE SGLSDVSRPS FCHSSCGHVS EGKRRFTYDH AELERKIACC

Homologie: Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 77%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FLT1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human FLT1

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FLT1

Target: FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Andere Bezeichnung: FLT1

Hintergrund: This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.
Protein Interaction Partner: SRPK1, VEGFA, Nedd4, UBC, ATR, NRP2, NRP1, VEGFB, PTK2B, PGF, PTK2, SHC1, NCK1, PLCG2, KDR, PTPN11, PLCG1, FLT1, YES1, CRK, FYN, CTNNB1, GRB2, SHC2, PIK3R1,
Protein Size: 463

Molekulargewicht: 50 kDa

Gen-ID: 2321

Pathways: RTK Signalweg, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals