Cathepsin K Antikörper (Middle Region)

Produktnummer ABIN2788629

Dieses Anti-Cathepsin K-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Cathepsin K in WB. Geeignet für Human, Ratte, Maus, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio) und Ziege.

Kurzübersicht für Cathepsin K Antikörper (Middle Region) (ABIN2788629)

Target: Cathepsin K (CTSK)

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathepsin K Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Cathepsin K Antikörper

Bindungsspezifität: Middle Region

Sequenz: SPQNLVDCVS ENDGCGGGYM TNAFQYVQKN RGIDSEDAYP YVGQEESCMY

Homologie: Cow: 100%, Dog: 100%, Goat: 82%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against CTSK. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CTSK

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 329 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Cathepsin K

Target: Cathepsin K (CTSK)

Andere Bezeichnung: CTSK

Hintergrund: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
Alias Symbols: CTS02, CTSO, CTSO1, CTSO2, MGC23107, PKND, PYCD
Protein Interaction Partner: LIG4, SERPINB13, SERPINB3, KNG1, SPARC, FGFR3,
Protein Size: 329

Molekulargewicht: 37 kDa

Gen-ID: 1513

NCBI Accession: NM_000396, NP_000387

UniProt: P43235

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades