WHSC2 Antikörper (N-Term)

Produktnummer ABIN2788623

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch WHSC2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd, Zebrafisch (Danio rerio) und Saccharomyces cerevisiae.

Kurzübersicht für WHSC2 Antikörper (N-Term) (ABIN2788623)

Target: WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd, Zebrafisch (Danio rerio), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WHSC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-WHSC2 Antikörper

Bindungsspezifität: N-Term

Sequenz: LLRKERGVKL LDISELDMVG AGREAKRRRK TLDAEVVEKP AKEETVVENA

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against WHSC2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human NELFA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu WHSC2

Target: WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))

Andere Bezeichnung: WHSC2

Hintergrund: This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93 % sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.
Alias Symbols: WHSC2, NELF-A, P/OKcl.15
Protein Size: 393

Molekulargewicht: 43 kDa

Gen-ID: 7469

NCBI Accession: NM_005663, NP_005654

UniProt: Q9H3P2

Pathways: Chromatin Binding