IL-21 Antikörper (C-Term)

Produktnummer ABIN2788558

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch IL-21 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Rind (Kuh), Pferd, Schwein, Hund, Ziege und Schaf.

Kurzübersicht für IL-21 Antikörper (C-Term) (ABIN2788558)

Target: IL-21 (IL21) (Interleukin 21 (IL21))

Reaktivität: Human, Rind (Kuh), Pferd, Schwein, Hund, Ziege, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IL-21 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: IL21 Antibody - C-terminal region

Sequenz: ERIINVSIKK LKRKPPSTNA GRRQKHRLTC PSCDSYEKKP PKEFLERFKS

Homologie: Cow: 79%, Dog: 86%, Goat: 86%, Horse: 79%, Human: 100%, Pig: 86%, Sheep: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against IL21. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human IL21

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60746-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu IL-21

Target: IL-21 (IL21) (Interleukin 21 (IL21))

Andere Bezeichnung: IL21

Hintergrund:

Background Information: This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative Symbols: Za11, IL-21, CVID11

Molekulargewicht: 16kDa

Gen-ID: 59067

NCBI Accession: NP_001193935

UniProt: Q9HBE4

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response