DTNBP1 Antikörper (C-Term)
Kurzübersicht für DTNBP1 Antikörper (C-Term) (ABIN2788443)
Target
Alle DTNBP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- DTNBP1 Antibody - C-terminal region
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Sequenz
- PESSTCQNEI TLQVPNPSEL RAKPPSSSST CTDSATRDIS EGGESPVVQS
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Homologie
- Cow: 79%, Human: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against DTNBP1. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human DTNBP1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60427-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))
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Andere Bezeichnung
- DTNBP1
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Hintergrund
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Background Information: This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Gene Name: dystrobrevin binding protein 1
Alternative Symbols: SDY, DBND, HPS7, My031, BLOC1S8
Protein Name: Dysbindin
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Molekulargewicht
- 29kDa
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Gen-ID
- 84062
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UniProt
- Q96EV8
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Pathways
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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