Cadherin 5 Antikörper (Middle Region)

Produktnummer ABIN2788335

Dieses Anti-Cadherin 5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Cadherin 5 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund und Meerschweinchen.

Kurzübersicht für Cadherin 5 Antikörper (Middle Region) (ABIN2788335)

Target: Cadherin 5 (CDH5)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Cadherin 5 Antikörper

Bindungsspezifität: Middle Region

Sequenz: SLFVEDPDEP QNRMTKYSIL RGDYQDAFTI ETNPAHNEGI IKPMKPLDYE

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CDH5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 784 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Cadherin 5

Target: Cadherin 5 (CDH5)

Andere Bezeichnung: CDH5

Hintergrund: This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.
Alias Symbols: 7B4, CD144, FLJ17376
Protein Interaction Partner: CTNNB1, MYC, P2RX4, P2RX6, PARD6A, SMG1, PKP4, F2RL2, CTNND1, SHC1, VIM, KDR, SRC, EPHA2, PTPRB, PTPN11, JUP, FGA, DSP, CSK, CTNNA1, FGB,
Protein Size: 784

Molekulargewicht: 83 kDa

Gen-ID: 1003

NCBI Accession: NM_001795, NP_001786

UniProt: P33151

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2